OSMO PatchOSMO Patch The OSMO Patch is designed to gently draw fluid from areas of the body where the patches are applied. OSMO Patch Application The OSMO Patch is simply positioned over the targeted area prior to going to sleep, where they then go to work removing fluid continually throughout the night while the individual sleeps. The patch is then removed and simply discarded in the morning and the process is repeated as required. Gently draws away fluid!