Septuagint - Torah - Paperbackby Scriptural Research Institute (Author) After the death of Alexander the Great in 323 BC, his generals ripped apart his empire, and by 305 BC General Ptolemy had gained control of the Eastern Mediterranean, including Egypt, Judea, Cyprus, Cyrene, and coastal regions of modern Turkey, including Cilicia, Pamphylia, Lycia, and Caria. He established the dynasty of the Ptolemies that would rule Egypt for the next three centuries until Cleopatra VII