Glucovance 250/1.25mg Tablets – Glibenclamide & Metformin for DiabetesGlucovance 250 1. 25mg Tablets Glucovance 250 1. 25mg Tablets combine Glibenclamide (a sulfonylurea) and Metformin (a biguanide) to effectively manage Type 2 diabetes mellitus. These two medications work together to improve glycemic control by lowering blood glucose levels in individuals whose diabetes is not adequately controlled by diet and exercise alone. Glibenclamide stimulates the pancreas to produce more insulin, helping to lower blood glucose