Panadol Night Tablets 24'sPanadol Night Tablets provide fast, effective relief from pain that is causing difficulty in getting to sleep such as headache, migraine, backache, rheumatic pain, muscle pain, period pain and toothache. It contains two active ingredients to relieve pain and help you get a good night's sleep: Paracetamol: a painkiller that can also help reduce a fever. Diphenhydramine hydrochloride: an antihistamine that causes sleepiness or drowsiness.